Relationships between the structural characteristic of curcumins that affect cell proliferation of hepatocarcinoma cells; [Relacions entre les caracterfstiques estructurals de les curcumines que afecten la proliferacio cellular de les cel-lules de /'hepatocarcinoma]; [Relaciones entre las caracteristicas estructurales de las curcuminas que afectan la proliferacion celular de las celulas de hepatocarcinoma]

2025-03-142025-03-14https://hdl.handle.net/20.500.12740/17477Relationships between the structural characteristic of curcumin and dimethoxycurcumin and their antitumoral activity were studied. Treatment of HepG2 cells for 24 h with the curcumin and dimethoxycurcumin resulted in apoptosis induction and dose-dependent inhibition of cell proliferation. The calculated docking and the DFT method, suggest a structure-activity relationship between the activities of dimethoxycurcumin and curcumin structure and the apoptosis in HepG2 cellsPDFCurcuminaHepatocarcinomaRelationships between the structural characteristic of curcumins that affect cell proliferation of hepatocarcinoma cells; [Relacions entre les caracterfstiques estructurals de les curcumines que afecten la proliferacio cellular de les cel-lules de /'hepatocarcinoma]; [Relaciones entre las caracteristicas estructurales de las curcuminas que afectan la proliferacion celular de las celulas de hepatocarcinoma]Artículohttps://doi.org/10.55815/417980