Vinicius Rodrigues de Lima, ErikErikVinicius Rodrigues de LimaOliveira Schwarz, Gustavo BernhardGustavo BernhardOliveira SchwarzHerpich, Fábio RafaelFábio RafaelHerpichAlmeida-Fernandes, FelipeFelipeAlmeida-FernandesNakazono, LilianneLilianneNakazonoDuarte Lacerda, Eduardo AlbertoEduardo AlbertoDuarte LacerdaSantos, AndréAndréSantosFigueiredo, André LuizAndré LuizFigueiredoGutiérrez-Soto, Luis AngelLuis AngelGutiérrez-SotoJobim Sartori, MariliaMariliaJobim SartoriFonseca-Faria, Marcos AntonioMarcos AntonioFonseca-FariaSampaio Carvalho, MaiaraMaiaraSampaio CarvalhoCubillos Palma, BárbaraBárbaraCubillos PalmaLösch, ElismarElismarLöschPardo Montaguth, GisselGisselPardo MontaguthSantos Silva, José YuriJosé YuriSantos SilvaLi, LianaLianaLiIzabela, MarinaMarinaIzabelaMagalhães Cardoso, NatanaelNatanaelMagalhães CardosoSantos-Silva, ThaisThaisSantos-SilvaLopes, Paulo Afranio AugustoPaulo Afranio AugustoLopesHumire, Pedro K.Pedro K.HumireVassallo Bordoni, RobertaRobertaVassallo BordoniReis Lopes, AmandaAmandaReis LopesSmith Castelli, Analia VivianaAnalia VivianaSmith CastelliKrabbe, Angela CristinaAngela CristinaKrabbeDamineli, AugustoAugustoDamineliFerreira Lopes, Carlos EduardoCarlos EduardoFerreira LopesLima-Dias, CiriaCiriaLima-Diasde Bom, Clecio RoqueClecio Roquede BomOlave-Rojas, Daniela E.Daniela E.Olave-RojasHazarika, DebasishDebasishHazarikaTelles, EduardoEduardoTellesGhuron, ErickErickGhuronLimberg, GuilhermeGuilhermeLimbergPerottoni, Helio D.Helio D.PerottoniThainá-Batista, JuliaJuliaThainá-BatistaSodré, LaerteLaerteSodréDoubrawa, LiaLiaDoubrawaBorges Fernandes, MarceloMarceloBorges FernandesMarinello, MuriloMuriloMarinelloPanda, SwayamtruptaSwayamtruptaPandaRé, Pierre AugustoPierre AugustoRéLopes de Oliveira, RaimundoRaimundoLopes de OliveiraRuiz Valença, RaquelRaquelRuiz ValençaDemarco, RicardoRicardoDemarcoCid-Fernandes, RobertoRobertoCid-FernandesFacundo Haack, RodrigoRodrigoFacundo HaackTorres-Flores, SergioSergioTorres-FloresAkras, StavrosStavrosAkrasBeers, Timothy C.Timothy C.BeersPlacco, Vinicius M.Vinicius M.PlaccoCernic, VitorVitorCernicSasse, Victor HugoVictor HugoSasseKanaan, AntonioAntonioKanaanRibeiro, TiagoTiagoRibeiroSchoenell, WilliamWilliamSchoenellMendes de Oliveira, Claudia LuciaClaudia LuciaMendes de OliveiraS-PLUS Collaboration2026-10-082026-10-082026-08-20Vinicius Rodrigues de Lima, Erik; Oliveira Schwarz, Gustavo Bernhard; Herpich, Fábio Rafael; Almeida-Fernandes, Felipe; Nakazono, Lilianne; Duarte Lacerda, Eduardo Alberto; Santos, André; Figueiredo, André Luiz; Gutiérrez-Soto, Luis Angel; Jobim Sartori, Marilia; Fonseca-Faria, Marcos Antonio; Sampaio Carvalho, Maiara; Cubillos Palma, Bárbara; Lösch, Elismar; Pardo Montaguth, Gissel; Santos Silva, José Yuri; Li, Liana; Izabela, Marina; Magalhães Cardoso, Natanael; Santos-Silva, Thais; Lopes, Paulo Afranio Augusto; Humire, Pedro K.; Vassallo Bordoni, Roberta; Reis Lopes, Amanda; Smith Castelli, Analia Viviana; Krabbe, Angela Cristina; Damineli, Augusto; Ferreira Lopes, Carlos Eduardo; Lima-Dias, Ciria; de Bom, Clecio Roque; Olave-Rojas, Daniela E.; Hazarika, Debasish; Telles, Eduardo; Ghuron, Erick; Limberg, Guilherme; Perottoni, Helio D.; Thainá-Batista, Julia; Sodré, Laerte; Doubrawa, Lia; Borges Fernandes, Marcelo; Marinello, Murilo; Panda, Swayamtrupta; Ré, Pierre Augusto; Lopes de Oliveira, Raimundo; Ruiz Valença, Raquel; Demarco, Ricardo; Cid-Fernandes, Roberto; Facundo Haack, Rodrigo; Torres-Flores, Sergio; Akras, Stavros; Beers, Timothy C.; Placco, Vinicius M.; Cernic, Vitor; Sasse, Victor Hugo; Kanaan, Antonio; Ribeiro, Tiago; Schoenell, William; Mendes de Oliveira, Claudia Lucia; S-PLUS Collaboration (2026-08-20). The S-PLUS Fifth Data Release: Over 4500 Square Degrees of the Southern Sky and a Multicolor View of the Hydra and Antlia Galaxy Clusters. The Astrophysical Journal, 1007(2), 167. https://doi.org/10.3847/1538-4357/ae8d1f0004-637X1538-4357https://hdl.handle.net/20.500.12740/24928Abstract We present the fifth data release (DR5) of the Southern Photometric Local Universe Survey (S-PLUS), covering 4592 deg 2 across 2491 fields. Observations were conducted with the T80-South, a Brazilian robotic telescope equipped with the Javalambre 12-filter system, containing five broadband and seven narrowband filters. Data products feature FITS images and extensive catalogs containing fluxes, magnitudes, and shape parameters for over 113 million detections. In addition, several value-added catalogs are provided, offering photometric redshifts (photo- zs ), object classifications, masks, and extinction coefficients. For the first time, this release includes coverage of 110 deg 2 along the Galactic disk, facilitating new research into Galactic structure and stellar populations. The release also provides full coverage of the Hydra Supercluster and numerous other nearby clusters with improved data reduction and calibration, enhancing photo- z accuracy, which is vital for large-scale structure studies. A preliminary analysis of the Hydra and Antlia galaxy clusters up to 5 × R 200 yields an updated catalog of 1706 cluster members based on both spectroscopic and high-quality photo- zs . Our photometric data shows that both clusters have a similar proportion of galaxies with an H α excess relative to their clustercentric distance, though Hydra has a higher fraction near its center. Additionally, the spatial distribution of all objects in our sample highlights a bridge connecting both clusters. We verify that S-PLUS DR5 provides a solid foundation for future scientific investigations, ranging from solar system studies to cosmology.http://purl.org/coar/access_right/c_abf2https://creativecommons.org/licenses/by/4.0/Galaxies: Formation, Evolution, PhenomenaAstronomy and Astrophysical ResearchStellar, planetary, and galactic studiesThe S-PLUS Fifth Data Release: Over 4500 Square Degrees of the Southern Sky and a Multicolor View of the Hydra and Antlia Galaxy ClustersArticulohttps://doi.org/10.3847/1538-4357/ae8d1f