The muometric wireless navigation system (MuWNS) is a technology enabling signal reception for machine controlling and communication systems underground where a radio or GPS signal would normally be lost. The penetrative power of muons in rock allows signal transmission from the surface down to 1.5–2.0 km of depth on Earth, depending on rock density. Such a depth would not be easily reached on the Moon and Mars, but an inflatable structure containing an artificial atmosphere would allow the muon production necessary for a thorough exploration and suitability assessment of existing lava tubes or borehole excavation to host a base. The density maps obtained by muography can also show the eventual presence of valuable metals, minerals, or water ice for in-situ resource utilization (ISRU). MuWNS’ broad spectrum of applications is crucial for the first deployment and then the correct functioning of an underground base on the Moon or Mars. © 2025 Elsevier B.V., All rights reserved.