In December 2019, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused a global pandemic with a high number of deaths and infected people worldwide. To contain the diffusion of coronavirus disease 2019 (COVID-19), several Governments have established a variety of control measures, such as the lockdown. As a result, daily activities, dietary habits, and physical activity changed during the COVID-19 lockdown, which could impact the cardiovascular risk profile of populations and, in particular, blood pressure (BP) in hypertensive subjects This systematic review was conducted to identify, appraise and synthesise the available studies on the impact of lockdown during the COVID-19 pandemic on BP in patients with hypertension.