Mo<inf>2</inf>TiC<inf>2</inf> MXene, a member of the expanding family of two-dimensional transition metal carbides, has emerged as a highly promising material owing to its unique layered structure, tunable surface chemistry, and excellent physicochemical properties. This review presents a detailed and focused analysis of Mo<inf>2</inf>TiC<inf>2</inf> MXene, with an emphasis on its synthesis strategies including conventional hydrofluoric acid-based and environmentally benign fluoride-free methods. Surface modifications and chemical functionalization approaches are discussed to highlight how these treatments enhance stability, dispersibility, and application-specific performance. Structural, mechanical, and thermoelectric characteristics are critically evaluated to establish a foundation for understanding the material's behavior under diverse conditions. The review further explores a wide range of applications, including its use in energy storage (supercapacitors, lithium-ion and sodium-ion batteries), energy conversion (photocatalytic hydrogen evolution and electrocatalysis for HER/ORR), and environmental remediation. Emerging applications in hydrogen storage, biomass conversion, sensing technologies, nonlinear photonics, and photocatalysis are also addressed. Recent theoretical insights based on DFT calculations are incorporated to provide atomic-level understanding of electronic structure, surface reactivity, and interaction mechanisms. Despite the promising advancements, challenges such as large-scale synthesis, structural stability, and limited exploration in biomedical and photothermal applications remain. Future research directions are outlined, including hybridization with other functional materials, advanced computational screening, and scalable green synthesis methods. By consolidating current progress and identifying critical knowledge gaps, this review serves as a timely and comprehensive resource, aimed at accelerating research on Mo<inf>2</inf>TiC<inf>2</inf> MXene for next-generation applications across energy, environment, and emerging technologies. © 2025 Elsevier B.V., All rights reserved.